MCP server

Guidetopharmacology

io.github.pipeworx-io/guidetopharmacology

Checked 28 Oct 2026, 09:03 UTC · Connected to it and listed its tools

IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) MCP — BYO key. Expert-curated pharmacology database of…

Website Source

At a glance

Type

MCP server

Publisher

pipeworx.io (verified by the MCP Registry)

Status

Working at last check

Tools

48

Token cost

About 28,959 tokens per request

Sets up in

Claude Code, Claude Desktop, Codex, Gemini CLI, Cursor, VS Code, Antigravity, ChatGPT, OpenAI API, Grok

Last checked

28 Oct 2026, 09:03 UTC

Connect it to your agent

Add to CursorAdd to VS CodeVS Code Insiders

Opens the app, which shows the server and asks you to confirm. For other apps, copy the setup below.

Claude Code

claude mcp add --transport http guidetopharmacology https://gateway.pipeworx.io/guidetopharmacology/mcp

Claude Desktop

Settings → Connectors → Add custom connector, and paste the URL.

Codex (config.toml)

[mcp_servers.guidetopharmacology]
url = "https://gateway.pipeworx.io/guidetopharmacology/mcp"

Gemini CLI

{"mcpServers":{"guidetopharmacology":{"httpUrl":"https://gateway.pipeworx.io/guidetopharmacology/mcp"}}}

Cursor

{"mcpServers":{"guidetopharmacology":{"url":"https://gateway.pipeworx.io/guidetopharmacology/mcp"}}}

VS Code

{"servers":{"guidetopharmacology":{"type":"http","url":"https://gateway.pipeworx.io/guidetopharmacology/mcp"}}}

Antigravity

agy mcp add guidetopharmacology https://gateway.pipeworx.io/guidetopharmacology/mcp

ChatGPT

Settings → Apps & Connectors → Advanced settings: turn on Developer mode, then Create a connector and paste the URL. Which plans can do this varies.

OpenAI API (Responses tools)

{"type":"mcp","server_label":"guidetopharmacology","server_url":"https://gateway.pipeworx.io/guidetopharmacology/mcp","require_approval":"always"}

Grok (xAI API tools)

{"type":"mcp","server_label":"guidetopharmacology","server_url":"https://gateway.pipeworx.io/guidetopharmacology/mcp"}

Tools

• ligand_interactions ~358 tokens
  What proteins a drug acts on — the curated target interactions for a ligand in the Guide to PHARMACOLOGY (IUPHAR/BPS), each with the target PROTEIN NAME, interaction type (Agonist/Antagonist/Inhibitor), action and binding affinity (pKi/pIC50). Pass the drug by name ("imatinib") and it is resolved fo
• search_ligands ~269 tokens
  Search the Guide to PHARMACOLOGY (IUPHAR/BPS) — an expert-curated pharmacology database — for drug ligands by name. Returns matching ligands with their GtoPdb ligand id, type (e.g. Synthetic organic, Peptide, Antibody, Metabolite), and approval status. Use the returned ligand id with ligand_interact
• search_targets ~268 tokens
  Search the Guide to PHARMACOLOGY (IUPHAR/BPS) — an expert-curated pharmacology database — for protein targets by name. Returns matching targets with their GtoPdb target id, abbreviation, and type (e.g. GPCR, CatalyticReceptor, Enzyme, Transporter). Use the returned target id with target_interactions
• target_interactions ~244 tokens
  List the quantitative ligand interactions for a protein target in the Guide to PHARMACOLOGY (IUPHAR/BPS). Given a GtoPdb target id (from search_targets), returns the ligands acting on it with interaction type (Agonist/Antagonist/Inhibitor/etc.), action, and binding affinity (e.g. pKi/pIC50). Require

Browse

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