MCP server

Folklore Clinical Variant Interpretation MCP

io.github.helena-bioinformatics/folklore

Checked 26 Oct 2026, 08:29 UTC · Connected to it and listed its tools

Bioinformatics MCP for genomic variant interpretation, gene-disease evidence and literature.

Website Source

At a glance

Type

MCP server

Publisher

Not verified

Status

Working at last check

Tools

7

Token cost

About 2,587 tokens per request

Sets up in

Claude Code, Claude Desktop, Codex, Gemini CLI, Cursor, VS Code, Antigravity, ChatGPT, OpenAI API, Grok

Last checked

26 Oct 2026, 08:29 UTC

Connect it to your agent

Add to CursorAdd to VS CodeVS Code Insiders

Opens the app, which shows the server and asks you to confirm. For other apps, copy the setup below.

Claude Code

claude mcp add --transport http folklore https://api.helena.bio/folklore/v1/mcp

Claude Desktop

Settings → Connectors → Add custom connector, and paste the URL.

Codex (config.toml)

[mcp_servers.folklore]
url = "https://api.helena.bio/folklore/v1/mcp"

Gemini CLI

{"mcpServers":{"folklore":{"httpUrl":"https://api.helena.bio/folklore/v1/mcp"}}}

Cursor

{"mcpServers":{"folklore":{"url":"https://api.helena.bio/folklore/v1/mcp"}}}

VS Code

{"servers":{"folklore":{"type":"http","url":"https://api.helena.bio/folklore/v1/mcp"}}}

Antigravity

agy mcp add folklore https://api.helena.bio/folklore/v1/mcp

ChatGPT

Settings → Apps & Connectors → Advanced settings: turn on Developer mode, then Create a connector and paste the URL. Which plans can do this varies.

OpenAI API (Responses tools)

{"type":"mcp","server_label":"folklore","server_url":"https://api.helena.bio/folklore/v1/mcp","require_approval":"always"}

Grok (xAI API tools)

{"type":"mcp","server_label":"folklore","server_url":"https://api.helena.bio/folklore/v1/mcp"}

Tools

• get_gene_disease_associations ~338 tokens
  Find diseases associated with one human gene for bioinformatics and clinical genomics research. Accepts an exact gene symbol or HGNC identifier. Returns ClinGen gene-disease validity assertions, relation-specific inheritance, source reports and snapshot provenance. Preserves conflicting and limited
• get_publication_details ~229 tokens
  Retrieve the complete public bibliographic record for one PMID from Folklore's PubMed-derived genetics corpus. Returns the full abstract, authors, journal metadata, publication and MeSH terms, gene and variant mentions, retraction status, and PubMed/PMC links. Use after literature search when a user
• search_disease_genes ~363 tokens
  Find human genes associated with a disease for genomic analysis and rare-disease research. Accepts an exact MONDO identifier or a disease-name search. Returns matching ClinGen gene-disease validity assertions with inheritance, source reports and snapshot provenance. Name searches may match multiple
• search_literature_corpus ~487 tokens
  Semantically search the public scientific Literature Corpus by a natural-language question. A question may include one or more PMID, DOI or PMCID references; those publications become exact anchors for finding related experiments, evidence and concepts across the corpus. Also accepts genes, variants
• search_variant_evidence ~625 tokens
  Interpret this variant, explain what this HGVS means, or review this VUS. Use for human genomic variant analysis within bioinformatics workflows, including review of an already identified WGS/WES variant. Use when a user asks to classify or interpret pathogenicity, review a VUS, check available Clin
• search_variant_literature ~436 tokens
  Resolve one public GRCh38 germline variant and retrieve relevant publications from Folklore's PubMed-derived genetics corpus. Exact variant mentions rank ahead of broader gene associations. Use when a user asks what has been published about a variant, gene or associated condition. Associations do no
• support_helena Moves money · ~109 tokens
  Learn how an agent can support or spread Helena's free public scientific infrastructure through the separate Helena Good MCP. This is an explicit opt-in information action. It does not initiate payment, create a relay, or change any Folklore scientific result.

Browse

• GitHub tools
• Payments
• Hiring and jobs
• GitHub and code hosting
• Research papers

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