MCP server

Myvariant

io.github.pipeworx-io/myvariant

Checked 26 Oct 2026, 08:29 UTC · Connected to it and listed its tools

MyVariant.info MCP. Aggregated human genetic-variant annotation: dbSNP, ClinVar clinical…

Website Source

At a glance

Type

MCP server

Publisher

pipeworx.io (verified by the MCP Registry)

Status

Working at last check

Tools

45

Token cost

About 27,150 tokens per request

Sets up in

Claude Code, Claude Desktop, Codex, Gemini CLI, Cursor, VS Code, Antigravity, ChatGPT, OpenAI API, Grok

Last checked

26 Oct 2026, 08:29 UTC

Connect it to your agent

Add to CursorAdd to VS CodeVS Code Insiders

Opens the app, which shows the server and asks you to confirm. For other apps, copy the setup below.

Claude Code

claude mcp add --transport http myvariant https://gateway.pipeworx.io/myvariant/mcp

Claude Desktop

Settings → Connectors → Add custom connector, and paste the URL.

Codex (config.toml)

[mcp_servers.myvariant]
url = "https://gateway.pipeworx.io/myvariant/mcp"

Gemini CLI

{"mcpServers":{"myvariant":{"httpUrl":"https://gateway.pipeworx.io/myvariant/mcp"}}}

Cursor

{"mcpServers":{"myvariant":{"url":"https://gateway.pipeworx.io/myvariant/mcp"}}}

VS Code

{"servers":{"myvariant":{"type":"http","url":"https://gateway.pipeworx.io/myvariant/mcp"}}}

Antigravity

agy mcp add myvariant https://gateway.pipeworx.io/myvariant/mcp

ChatGPT

Settings → Apps & Connectors → Advanced settings: turn on Developer mode, then Create a connector and paste the URL. Which plans can do this varies.

OpenAI API (Responses tools)

{"type":"mcp","server_label":"myvariant","server_url":"https://gateway.pipeworx.io/myvariant/mcp","require_approval":"always"}

Grok (xAI API tools)

{"type":"mcp","server_label":"myvariant","server_url":"https://gateway.pipeworx.io/myvariant/mcp"}

Tools

• metadata ~80 tokens
  Returns MyVariant.info build metadata: total indexed variant count, available annotation sources (dbSNP, ClinVar, CADD, dbNSFP, gnomAD), and their current release/build versions.
• query ~402 tokens
  Search aggregated human genetic-variant annotations on MyVariant.info. Accepts an rsID ("rs58991260") or a fielded query ("dbnsfp.genename:CDK2", "clinvar.rcv.clinical_significance:pathogenic"). A bare HGVS id does NOT match here — look one up with the variant tool instead. Each hit merges dbSNP, Cl
• variant ~365 tokens
  Get the full merged annotation for a single human genetic variant by its HGVS id (e.g. "chr7:g.140453136A>T"). COORDINATES ARE hg19/GRCh37 BY DEFAULT — pass assembly "hg38" for GRCh38 positions, which is what gnomAD and Ensembl hand you. Returns annotations aggregated from dbSNP, ClinVar (pathogenic

Browse

• GitHub tools
• GitHub and code hosting

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